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dc.contributor.authorJuchler, Norman-
dc.contributor.authorSchilling, Sabine-
dc.contributor.authorVartan, Kurtcuoglu-
dc.contributor.authorHirsch, Sven-
dc.date.accessioned2018-10-23T14:35:13Z-
dc.date.available2018-10-23T14:35:13Z-
dc.date.issued2016-09-15-
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/12073-
dc.description.abstractThe risk assessment of intracranial aneurysms is an exceedingly difficult task. Clinicians associate aneurysm shape irregularity with disease instability. However, there is no consensus on which shape features reliably predict aneurysm instability. We have adopted a machine learning approach to identify shape features with predictive power for aneurysm instability: From imaging data 3D models of aneurysms are extracted that are used to train a classifier. A variety of representations of the 3D shape are calculated, these include the Zernike moment invariants (ZMI) and geometry indices such as aspect ratio, ellipticity and non-sphericity. The processing pipeline was applied to synthetic data and clinical datasets of 413 aneurysms registered in the AneurysmDataBase (SwissNeuroFoundation) and AneuriskWeb database. Classification based on ZMI alone allowed us to distinguish between sidewall and bifurcation aneurysms, but failed to forecast an aneurysm’s rupture status reliably. Simpler geometry indices performed similarly well in rupture status prediction. On synthetic data we showed that ZMI could encode shape irregularity. It remains to be investigated whether further stratification of the aneurysms in terms of location, size and clinical factors will increase the robustness of the applied classification methods.de_CH
dc.language.isoende_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectShape-based risk assessmentde_CH
dc.subjectIntracranial aneurysmsde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleShape-based assessment of intracranial aneurysm disease statusde_CH
dc.typeKonferenz: Posterde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Computational Life Sciences (ICLS)de_CH
zhaw.conference.detailsZNZ Symposium 2016, Zurich, 15. September 2016de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.publication.reviewNot specifiedde_CH
zhaw.webfeedBiomedical Simulationde_CH
zhaw.webfeedMedical Image Analysis & Data Modelingde_CH
zhaw.funding.zhawAneuXde_CH
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Juchler, N., Schilling, S., Vartan, K., & Hirsch, S. (2016, September 15). Shape-based assessment of intracranial aneurysm disease status. ZNZ Symposium 2016, Zurich, 15. September 2016.
Juchler, N. et al. (2016) ‘Shape-based assessment of intracranial aneurysm disease status’, in ZNZ Symposium 2016, Zurich, 15. September 2016.
N. Juchler, S. Schilling, K. Vartan, and S. Hirsch, “Shape-based assessment of intracranial aneurysm disease status,” in ZNZ Symposium 2016, Zurich, 15. September 2016, Sep. 2016.
JUCHLER, Norman, Sabine SCHILLING, Kurtcuoglu VARTAN und Sven HIRSCH, 2016. Shape-based assessment of intracranial aneurysm disease status. In: ZNZ Symposium 2016, Zurich, 15. September 2016. Conference poster. 15 September 2016
Juchler, Norman, Sabine Schilling, Kurtcuoglu Vartan, and Sven Hirsch. 2016. “Shape-Based Assessment of Intracranial Aneurysm Disease Status.” Conference poster. In ZNZ Symposium 2016, Zurich, 15. September 2016.
Juchler, Norman, et al. “Shape-Based Assessment of Intracranial Aneurysm Disease Status.” ZNZ Symposium 2016, Zurich, 15. September 2016, 2016.


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