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https://doi.org/10.21256/zhaw-4814| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents? |
| Autor/-in: | Dratva, Julia Caviezel, Seraina Schaffner, Emmanuel Stolz, Daiana Rothe, Thomas Kuenzli, Nino Schmidt-Trucksäss, Arno Zemp, Elisabeth Probst-Hensch, Nicole |
| DOI: | 10.21256/zhaw-4814 10.1007/s00431-018-3107-0 |
| Erschienen in: | European Journal of Pediatrics |
| Band(Heft): | 177 |
| Heft: | 5 |
| Seite(n): | 699 |
| Seiten bis: | 707 |
| Erscheinungsdatum: | 6-Feb-2018 |
| Verlag / Hrsg. Institution: | Springer |
| ISSN: | 0340-6199 1432-1076 |
| Sprache: | Englisch |
| Schlagwörter: | Asthma; Atherosclerosis; Carotid intima media thickness; Epidemiology; Adolescent; Asthma; Atherosclerosis; Carotid Arteries; Child; Cross-Sectional Studies; Female; Humans; Male; Risk Factors; Switzerland; Carotid Intima-Media Thickness; Sex Factors |
| Fachgebiet (DDC): | 616: Innere Medizin und Krankheiten 618.92: Pädiatrie |
| Zusammenfassung: | Respiratory diseases are associated with increased cardiovascular risk in adults, but little is known on the early impact on the vasculature in youth. The SAPALDIA Youth study, the offspring study of the Swiss Study on Air Pollution and Lung and Heart Disease In Adults (SAPALDIA), investigated the association between physician-diagnosed asthma status and common carotid artery intima media thickness (CIMT). Offspring underwent standardized clinical protocols and provided information on early life factors, health, and lifestyle. The association between per subject averages of CIMT and asthma was estimated using mixed linear regression analyses adjusting for main confounders, testing for interaction with gender and age. Of 257 offspring (mean age 15 years, 53% female), 11.5% reported doctor-diagnosed asthma (male 17%, female 7%). Mean CIMT was significantly different by gender (male 0.53 mm (± 0.045), female 0.50 mm (± 0.048); p < 0.001). Interaction was highly significant by gender (p = 0.001) with significantly increased CIMT in asthmatic vs. non-asthmatics boys (difference 0.023 mm, 95% CI 0.003; 0.043), as compared to girls. Conclusion: Our study suggests an increased risk for early vascular change in adolescent asthmatic boys. Whereas the small number of girls limits the interpretation, the result necessitates further research into sex-specific atherosclerotic burden related to respiratory health in adolescence. |
| Weitere Angaben: | Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/10833 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Gesperrt bis: | 2023-05-01 |
| Departement: | Gesundheit |
| Organisationseinheit: | Institut für Public Health (IPH) |
| Enthalten in den Sammlungen: | Publikationen Gesundheit |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| 2018_Dratva_Is_There_A_Gender_specific_Association_between_asthma.pdf | 563.55 kB | Adobe PDF |  Öffnen/Anzeigen |
Zur Langanzeige
Dratva, J., Caviezel, S., Schaffner, E., Stolz, D., Rothe, T., Kuenzli, N., Schmidt-Trucksäss, A., Zemp, E., & Probst-Hensch, N. (2018). Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents? European Journal of Pediatrics, 177(5), 699–707. https://doi.org/10.21256/zhaw-4814
Dratva, J. et al. (2018) ‘Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents?’, European Journal of Pediatrics, 177(5), pp. 699–707. Available at: https://doi.org/10.21256/zhaw-4814.
J. Dratva et al., “Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents?,” European Journal of Pediatrics, vol. 177, no. 5, pp. 699–707, Feb. 2018, doi: 10.21256/zhaw-4814.
DRATVA, Julia, Seraina CAVIEZEL, Emmanuel SCHAFFNER, Daiana STOLZ, Thomas ROTHE, Nino KUENZLI, Arno SCHMIDT-TRUCKSÄSS, Elisabeth ZEMP und Nicole PROBST-HENSCH, 2018. Is there a gender-specific association between asthma and carotid intima media thickness in Swiss adolescents? European Journal of Pediatrics. 6 Februar 2018. Bd. 177, Nr. 5, S. 699–707. DOI 10.21256/zhaw-4814
Dratva, Julia, Seraina Caviezel, Emmanuel Schaffner, Daiana Stolz, Thomas Rothe, Nino Kuenzli, Arno Schmidt-Trucksäss, Elisabeth Zemp, and Nicole Probst-Hensch. 2018. “Is There a Gender-Specific Association between Asthma and Carotid Intima Media Thickness in Swiss Adolescents?” European Journal of Pediatrics 177 (5): 699–707. https://doi.org/10.21256/zhaw-4814.
Dratva, Julia, et al. “Is There a Gender-Specific Association between Asthma and Carotid Intima Media Thickness in Swiss Adolescents?” European Journal of Pediatrics, vol. 177, no. 5, Feb. 2018, pp. 699–707, https://doi.org/10.21256/zhaw-4814.
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