Showing results 17 to 36 of 46
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Issue Date | Title | Involved Person(s) |
Jan-2017 | How to use Computational Fluid Dynamics in the development of cell therapeutics | Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter |
2021 | Human adipose stem cells (hASCs) grown on biodegradable microcarriers in serum- and xeno-free medium preserve their undifferentiated status | Muoio, Francesco; Panella, Stefano; Jossen, Valentin; Lindner, Matias; Harder, Yves, et al |
Sep-2016 | Impact of shear stress on cell growth and microcarrier-cell-agglomerate formation in microcarrier-based cultivations of adipose tissue-derived stromal/stem cells | Jossen, Valentin; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter |
Jun-2013 | Investigations of fluif flow and microcarrier suspension for hMSC expansion in single-use stirred bioreactors | Jossen, Valentin; Kaiser, Stephan; Schirmaier, Carmen; van den Bos, Christian; Eibl, Dieter, et al |
2018 | Manufacturing human mesenchymal stem cells at clinical scale : process and regulatory challenges | Jossen, Valentin; van den Bos, Christian; Eibl-Schindler, Regine; Eibl, Dieter |
2015 | Mass production of hMSCs : an approach based on stirred single-use bioreactors | Eibl-Schindler, Regine; Jossen, Valentin; Eibl, Dieter |
26-Nov-2014 | Mass production of mesenchymal stem cells — impact of bioreactor design and flow conditions on proliferation and differentiation | Jossen, Valentin; Pörtner, Ralf; Kaiser, Stephan C.; Kraume, Matthias; Eibl, Dieter, et al |
Jun-2014 | Microcarrier-based expansion of adipose tissue and bone marrow derived human mesenchymal stem cells in therapeutically relevant doses | Jossen, Valentin; Ott, Anita; Kaiser, Stephan; Brill, Silke; Spicker, Sonja, et al |
2014 | Modification and qualification of a stirred single-use bioreactor for the improved expansion of human mesenchymal stem cells at benchtop scale | Jossen, Valentin; Kaiser, Stephan C.; Schirmaier, Carmen; Hermann, Jacqueline; Tappe, Alexander, et al |
Mar-2018 | Multiphase CFD simulations for supporting MC-based hMSC process development | Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter |
May-2016 | Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale | Demuth, Caspar; Varonier, Joel; Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter |
23-Oct-2020 | Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells | Jossen, Valentin; Eibl, Dieter; Eibl, Regine |
2014 | Numerische Strömungsuntersuchungen für die Massstabsübertragung der Expansion von humanen mesenchymalen Stammzellen in gerührten Single-Use Bioreaktoren | Jossen, Valentin; Kaiser, Stephan; Eibl-Schindler, Regine; Eibl, Dieter |
19-Sep-2016 | Nutzung von Sensor Spots zur Bestimmung der Gelöstsauerstoffkonzentration in Single-use Systemen im Labormassstab | Maschke, Rüdiger; Werner, Sören; Stalder, Mischa; Jossen, Valentin; Eibl, Dieter |
Jun-2015 | On-line-pH- und -DO-Messungen in Mikrocarrier-basierter hMSC Kultur | Jossen, Valentin; Schirmaier, Carmen; John, Gernot T.; Eibl, Dieter; Eibl-Schindler, Regine |
Sep-2014 | Online pH and DO measurement in microcarrier-based hMSC cultivations performed in single-use spinner flask | Jossen, Valentin; Schirmaier, Carmen; John, Gernot; Siehoff, Ann; Eibl, Dieter, et al |
2014 | Optimization of a benchtop single-use bioreactor for the expansion of adipose-tissue and bone marrow derived human mesenchymal stem cells | Jossen, Valentin; Kaiser, Stephan; Ott, Anita; Siehoff, Ann; Brill, Silke, et al |
May-2016 | Overview : single-use technologies in biopharmaceutical manufacturing | Jossen, Valentin |
7-Dec-2020 | Oxygen mass transfer in biopharmaceutical processes : numerical and experimental approaches | Seidel, Stefan; Maschke, Rüdiger; Werner, Sören; Jossen, Valentin; Eibl, Dieter |
2018 | Power input measurements in stirred bioreactors at laboratory scale | Kaiser, Stephan C.; Werner, Sören; Jossen, Valentin; Blaschczok, Katharina; Eibl, Dieter |