| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Fluorescence reporters for phosphodiesterase activity |
| Authors: | Berkessel, Albrecht Riedl, Rainer |
| DOI: | 10.1002/anie.199714811 |
| Published in: | Angewandte Chemie: International Edition |
| Volume(Issue): | 36 |
| Issue: | 13-14 |
| Page(s): | 1481 |
| Pages to: | 1483 |
| Issue Date: | 1997 |
| Publisher / Ed. Institution: | Wiley |
| ISSN: | 1433-7851 0570-0833 |
| Language: | English |
| Subjects: | Fluorescence Reporter |
| Subject (DDC): | 615: Pharmacology and therapeutics |
| Abstract: | A sensitive indicator of nuclease activity is the fluorescence behavior of phosphodiesters 1 and 2. Although 1 and 2 do not fluoresce due to intramolecular quenching, the strongly fluorescent naphthyl phosphates and naphthols are liberated upon hydrolysis. This gives rise to an extremely strong increase in fluorescence intensity. Combined application of 1 and 2 allows detection of phosphatase in addition to phosphodiesterase activity. f = fluorophore, q = quencher. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2831 |
| Fulltext version: | Published version |
| License (according to publishing contract): | Licence according to publishing contract |
| Departement: | Life Sciences and Facility Management |
| Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
| Appears in collections: | Publikationen Life Sciences und Facility Management |
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Berkessel, A., & Riedl, R. (1997). Fluorescence reporters for phosphodiesterase activity. Angewandte Chemie: International Edition, 36(13-14), 1481–1483. https://doi.org/10.1002/anie.199714811
Berkessel, A. and Riedl, R. (1997) ‘Fluorescence reporters for phosphodiesterase activity’, Angewandte Chemie: International Edition, 36(13-14), pp. 1481–1483. Available at: https://doi.org/10.1002/anie.199714811.
A. Berkessel and R. Riedl, “Fluorescence reporters for phosphodiesterase activity,” Angewandte Chemie: International Edition, vol. 36, no. 13-14, pp. 1481–1483, 1997, doi: 10.1002/anie.199714811.
BERKESSEL, Albrecht und Rainer RIEDL, 1997. Fluorescence reporters for phosphodiesterase activity. Angewandte Chemie: International Edition. 1997. Bd. 36, Nr. 13-14, S. 1481–1483. DOI 10.1002/anie.199714811
Berkessel, Albrecht, and Rainer Riedl. 1997. “Fluorescence Reporters for Phosphodiesterase Activity.” Angewandte Chemie: International Edition 36 (13-14): 1481–83. https://doi.org/10.1002/anie.199714811.
Berkessel, Albrecht, and Rainer Riedl. “Fluorescence Reporters for Phosphodiesterase Activity.” Angewandte Chemie: International Edition, vol. 36, no. 13-14, 1997, pp. 1481–83, https://doi.org/10.1002/anie.199714811.
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