1. ZHAW digitalcollection
  2. School of Engineering
  3. Publikationen
  4. Publikationen School of Engineering
Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1651
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMiyashita, Shuhei-
dc.contributor.authorAudretsch, Christof-
dc.contributor.authorNagy, Zoltán-
dc.contributor.authorFüchslin, Rudolf Marcel-
dc.contributor.authorPfeifer, Rolf-
dc.date.accessioned2018-02-08T10:39:14Z-
dc.date.available2018-02-08T10:39:14Z-
dc.date.issued2015-
dc.identifier.issn1742-5689de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2700-
dc.description.abstractEnzymes play important roles in catalysing biochemical transaction paths, acting as logical machines through the morphology of the processes. A key challenge in elucidating the nature of these systems, and for engineering manufacturing methods inspired by biochemical reactions, is to attain a comprehensive understanding of the stereochemical ground rules of enzymatic reactions. Here, we present a model of catalysis that can be performed magnetically by centimetre-sized passive floating units. The designed system, which is equipped with permanent magnets only, passively obeys the local causalities imposed by magnetic interactions, albeit it shows a spatial behaviour and an energy profile analogous to those of biochemical enzymes. In this process, the enzyme units trigger physical conformation changes of the target by levelling out the magnetic potential barrier (activation potential) to a funnel type and, thus, induce cascading conformation changes of the targeted substrate units reacting in parallel. The inhibitor units, conversely, suppress such changes by increasing the potential. Because the model is purely mechanical and established on a physics basis in the absence of turbulence, each performance can be explained by the morphology of the unit, extending the definition of catalysis to systems of alternative scales.de_CH
dc.language.isoende_CH
dc.publisherThe Royal Societyde_CH
dc.relation.ispartofJournal of the Royal Society Interfacede_CH
dc.rightshttp://creativecommons.org/licenses/by-nc/4.0/de_CH
dc.subjectMagnetic catalysisde_CH
dc.subjectEnzymede_CH
dc.subjectInhibitorde_CH
dc.subjectConformation changede_CH
dc.subjectAutocatalysisde_CH
dc.subjectReaction phasede_CH
dc.subject.ddc540: Chemiede_CH
dc.subject.ddc572: Biochemiede_CH
dc.titleMechanical catalysis on the centimetre scalede_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
dc.identifier.doi10.21256/zhaw-1651-
dc.identifier.doi10.1098/rsif.2014.1271de_CH
zhaw.funding.euNode_CH
zhaw.issue104de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume12de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in collections:Publikationen School of Engineering

Files in This Item:
File Description SizeFormat 
2015_Miyashita_Mechanical catalysis on the centimetre scale_Journal of the Royal Society.pdf989.96 kBAdobe PDFThumbnail
View/Open
Show simple item record
Miyashita, S., Audretsch, C., Nagy, Z., Füchslin, R. M., & Pfeifer, R. (2015). Mechanical catalysis on the centimetre scale. Journal of the Royal Society Interface, 12(104). https://doi.org/10.21256/zhaw-1651
Miyashita, S. et al. (2015) ‘Mechanical catalysis on the centimetre scale’, Journal of the Royal Society Interface, 12(104). Available at: https://doi.org/10.21256/zhaw-1651.
S. Miyashita, C. Audretsch, Z. Nagy, R. M. Füchslin, and R. Pfeifer, “Mechanical catalysis on the centimetre scale,” Journal of the Royal Society Interface, vol. 12, no. 104, 2015, doi: 10.21256/zhaw-1651.
MIYASHITA, Shuhei, Christof AUDRETSCH, Zoltán NAGY, Rudolf Marcel FÜCHSLIN und Rolf PFEIFER, 2015. Mechanical catalysis on the centimetre scale. Journal of the Royal Society Interface. 2015. Bd. 12, Nr. 104. DOI 10.21256/zhaw-1651
Miyashita, Shuhei, Christof Audretsch, Zoltán Nagy, Rudolf Marcel Füchslin, and Rolf Pfeifer. 2015. “Mechanical Catalysis on the Centimetre Scale.” Journal of the Royal Society Interface 12 (104). https://doi.org/10.21256/zhaw-1651.
Miyashita, Shuhei, et al. “Mechanical Catalysis on the Centimetre Scale.” Journal of the Royal Society Interface, vol. 12, no. 104, 2015, https://doi.org/10.21256/zhaw-1651.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.