Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients

Petersen, Jens A.; Spiess, Martina; Curt, Armin; Dietz, Volker; Schubert, Martin

doi:10.1177/1545968312438437

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients
Authors:	Petersen, Jens A. Spiess, Martina Curt, Armin Dietz, Volker Schubert, Martin
et. al:	No
DOI:	10.1177/1545968312438437
Published in:	Neurorehabilitation and Neural Repair
Volume(Issue):	26
Issue:	8
Page(s):	939
Pages to:	948
Issue Date:	Oct-2012
Publisher / Ed. Institution:	Sage
ISSN:	1545-9683 1552-6844
Language:	English
Subjects:	Adult; Electromyography; Evoked otential, motor; Female; Humans; Leg; Linear models; Longitudinal study; Male; Middle aged; Muscle, skeletal; Neural conduction; Prospective study; Reaction time; Recovery of function; Retrospective study; Spinal cord injuries; Tibial nerve; Transcranial magnetic stimulation; Walking
Subject (DDC):	616.8: Neurology, diseases of nervous system 617: Surgery
Abstract:	Background: The description of the natural course of recovery from a spinal cord injury (SCI) with spontaneous improvement of neurological, neurophysiological, and functional measures is an important prerequisite in appraising effects of upcoming interventional therapies. Objective: To describe the spontaneous evolution of motor-evoked potentials of the anterior tibial muscle (TA-MEP) and their relation to outcomes of lower extremity motor scores (LEMS) and walking function in patients recovering from an acute SCI. Methods: TA-MEPs were assessed in 255 SCI subjects within 5 time intervals throughout the first year after SCI with combined neurological and functional measures. Tibial nerve conduction studies were performed to screen for peripheral nerve damage. Results: TA-MEP allowed stratification of SCI according to lesion severity and outcome. As MEP amplitudes increased over 12 months after SCI, this was paralleled by a significant improvement of LEMS and walking function. TA-MEP latencies remained usually stable. Conclusion: Clinical outcome and walking function after SCI can be predicted independent of clinical measures by assessment of TA-MEP reflecting corticospinal tract integrity.
URI:	https://digitalcollection.zhaw.ch/handle/11475/25583
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Health Sciences
Organisational Unit:	Institute of Occupational Therapy (IER)
Appears in collections:	Publikationen Gesundheit

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Petersen, J. A., Spiess, M., Curt, A., Dietz, V., & Schubert, M. (2012). Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients. Neurorehabilitation and Neural Repair, 26(8), 939–948. https://doi.org/10.1177/1545968312438437

Petersen, J.A. et al. (2012) ‘Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients’, Neurorehabilitation and Neural Repair, 26(8), pp. 939–948. Available at: https://doi.org/10.1177/1545968312438437.

J. A. Petersen, M. Spiess, A. Curt, V. Dietz, and M. Schubert, “Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients,” Neurorehabilitation and Neural Repair, vol. 26, no. 8, pp. 939–948, Oct. 2012, doi: 10.1177/1545968312438437.

PETERSEN, Jens A., Martina SPIESS, Armin CURT, Volker DIETZ und Martin SCHUBERT, 2012. Spinal cord injury : one-year evolution of motor-evoked potentials and recovery of leg motor function in 255 patients. Neurorehabilitation and Neural Repair. Oktober 2012. Bd. 26, Nr. 8, S. 939–948. DOI 10.1177/1545968312438437

Petersen, Jens A., Martina Spiess, Armin Curt, Volker Dietz, and Martin Schubert. 2012. “Spinal Cord Injury : One-Year Evolution of Motor-Evoked Potentials and Recovery of Leg Motor Function in 255 Patients.” Neurorehabilitation and Neural Repair 26 (8): 939–48. https://doi.org/10.1177/1545968312438437.

Petersen, Jens A., et al. “Spinal Cord Injury : One-Year Evolution of Motor-Evoked Potentials and Recovery of Leg Motor Function in 255 Patients.” Neurorehabilitation and Neural Repair, vol. 26, no. 8, Oct. 2012, pp. 939–48, https://doi.org/10.1177/1545968312438437.