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dc.contributor.authorZipser, Carl Moritz-
dc.contributor.authorDeuel, Jeremy-
dc.contributor.authorErnst, Jutta-
dc.contributor.authorSchubert, Maria-
dc.contributor.authorvon Känel, Roland-
dc.contributor.authorBöttger, Sönke-
dc.date.accessioned2019-07-17T09:07:01Z-
dc.date.available2019-07-17T09:07:01Z-
dc.date.issued2019-
dc.identifier.issn0001-6268de_CH
dc.identifier.issn0942-0940de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/17507-
dc.description.abstractBackground: Delirium is the most common neuropsychiatric presentation during hospitalization. In neurosurgery, studies on predisposing and precipitating risk factors for the development of delirium are rare but required for the individual risk estimation. Methods: Prospective cohort study in a tertiary university center. In total, 949 neurosurgical patients, 307 with and 642 without delirium, were included. Demographic factors, neurosurgery-related, neurological, and medical clusters were tested as predictors of delirium in multiple logistic regression analyses. Results: The incidence of delirium in this cohort of neurosurgical patients was 32.4%. Compared to patients without delirium, those with delirium were significantly older, more cognitively and neurologically impaired, transferred from hospitals and nursing homes, admitted as emergencies, longer hospitalized (16.2 vs. 9.5 days; p < 0.001), in greater need of intensive care management, and more frequently transferred to rehabilitation. Predisposing factors of delirium were stroke (OR 5.45, CI 2.12–14.0, p < 0.001), cardiac insufficiency (OR 4.59, CI 1.09–19.26, p = 0.038), cerebral neoplasm (OR 1.53, CI 0.92–2.54, p = 0.019), and age ≥ 65 years (OR 1.47, CI 1.03–2.09, p = 0.030). Precipitating factors of delirium were acute cerebral injury (OR 3.91, CI 2.24–6.83, p < 0.001), hydrocephalus (OR 3.10, CI 1.98–4.87, p < 0.001), and intracranial hemorrhage (OR 1.90, CI 1.23–2.94, p = 0.004). Conclusions: Delirium in acute neurosurgical patients was associated with longer hospitalization. Whereas common etiologies of delirium like infections and dementia, did not predict delirium, preexisting neurovascular and traumatic diseases, as well as surgery-related events seem important risk factors contributing to delirium in neurosurgery.de_CH
dc.language.isoende_CH
dc.publisherSpringerde_CH
dc.relation.ispartofActa Neurochirurgicade_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectDeliriumde_CH
dc.subjectImpactde_CH
dc.subjectInteractionde_CH
dc.subjectNeurosurgeryde_CH
dc.subjectPrecipitating factorde_CH
dc.subjectPredisposing factorde_CH
dc.subjectRisk factorde_CH
dc.subject.ddc617: Chirurgiede_CH
dc.titleThe predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patientsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Pflege (IPF)de_CH
dc.identifier.doi10.1007/s00701-019-03927-zde_CH
dc.identifier.pmid31106393de_CH
zhaw.funding.euNode_CH
zhaw.issue7de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end1315de_CH
zhaw.pages.start1307de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume161de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
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Zipser, C. M., Deuel, J., Ernst, J., Schubert, M., von Känel, R., & Böttger, S. (2019). The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients. Acta Neurochirurgica, 161(7), 1307–1315. https://doi.org/10.1007/s00701-019-03927-z
Zipser, C.M. et al. (2019) ‘The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients’, Acta Neurochirurgica, 161(7), pp. 1307–1315. Available at: https://doi.org/10.1007/s00701-019-03927-z.
C. M. Zipser, J. Deuel, J. Ernst, M. Schubert, R. von Känel, and S. Böttger, “The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients,” Acta Neurochirurgica, vol. 161, no. 7, pp. 1307–1315, 2019, doi: 10.1007/s00701-019-03927-z.
ZIPSER, Carl Moritz, Jeremy DEUEL, Jutta ERNST, Maria SCHUBERT, Roland VON KÄNEL und Sönke BÖTTGER, 2019. The predisposing and precipitating risk factors for delirium in neurosurgery : a prospective cohort study of 949 patients. Acta Neurochirurgica. 2019. Bd. 161, Nr. 7, S. 1307–1315. DOI 10.1007/s00701-019-03927-z
Zipser, Carl Moritz, Jeremy Deuel, Jutta Ernst, Maria Schubert, Roland von Känel, and Sönke Böttger. 2019. “The Predisposing and Precipitating Risk Factors for Delirium in Neurosurgery : A Prospective Cohort Study of 949 Patients.” Acta Neurochirurgica 161 (7): 1307–15. https://doi.org/10.1007/s00701-019-03927-z.
Zipser, Carl Moritz, et al. “The Predisposing and Precipitating Risk Factors for Delirium in Neurosurgery : A Prospective Cohort Study of 949 Patients.” Acta Neurochirurgica, vol. 161, no. 7, 2019, pp. 1307–15, https://doi.org/10.1007/s00701-019-03927-z.


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