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https://doi.org/10.21256/zhaw-14456| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | A three-generation study on the association of tobacco smoking with asthma |
| Autor/-in: | Accordini, Simone Calciano, Lucia Johannessen, Ane Portas, Laura Benediktsdóttir, Bryndis Bertelsen, Randi Jacobsen Bråbäck, Lennart Carsin, Anne-Elie Dharmage, Shyamali C Dratva, Julia Forsberg, Bertil Gomez Real, Francisco Heinrich, Joachim Holloway, John W Holm, Mathias Janson, Christer Jögi, Rain Leynaert, Bénédicte Malinovschi, Andrei Marcon, Alessandro Martínez-Moratalla Rovira, Jesús Raherison, Chantal Sánchez-Ramos, José Luis Schlünssen, Vivi Bono, Roberto Corsico, Angelo G Demoly, Pascal Dorado Arenas, Sandra Nowak, Dennis Pin, Isabelle Weyler, Joost Jarvis, Deborah Svanes, Cecilie |
| DOI: | 10.1093/ije/dyy031 10.21256/zhaw-14456 |
| Erschienen in: | International Journal of Epidemiology |
| Band(Heft): | 47 |
| Heft: | 4 |
| Seite(n): | 1106 |
| Seiten bis: | 1117 |
| Erscheinungsdatum: | 2018 |
| Verlag / Hrsg. Institution: | Oxford University Press |
| ISSN: | 0300-5771 1464-3685 |
| Sprache: | Englisch |
| Fachgebiet (DDC): | 616: Innere Medizin und Krankheiten |
| Zusammenfassung: | Background: Mothers’ smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers’ smoking may have a similar effect, and biological plausibility that fathers’ smoking during adolescence may influence offspring’s health through transmittable epigenetic changes in sperm precursor cells. We evaluated the three-generation associations of tobacco smoking with asthma. Methods: Between 2010 and 2013, at the European Community Respiratory Health Survey III clinical interview, 2233 mothers and 1964 fathers from 26 centres reported whether their offspring (aged ≤51 years) had ever had asthma and whether it had coexisted with nasal allergies or not. Mothers and fathers also provided information on their parents’ (grandparents) and their own asthma, education and smoking history. Multilevel mediation models within a multicentre three-generation framework were fitted separately within the maternal (4666 offspring) and paternal (4192 offspring) lines. Results: Fathers’ smoking before they were 15 [relative risk ratio (RRR) = 1.43, 95% confidence interval (CI): 1.01–2.01] and mothers’ smoking during pregnancy (RRR = 1.27, 95% CI: 1.01-1.59) were associated with asthma without nasal allergies in their offspring. Grandmothers’ smoking during pregnancy was associated with asthma in their daughters [odds ratio (OR) = 1.55, 95% CI: 1.17-2.06] and with asthma with nasal allergies in their grandchildren within the maternal line (RRR = 1.25, 95% CI: 1.02-1.55). Conclusions: Fathers’ smoking during early adolescence and grandmothers’ and mothers’ smoking during pregnancy may independently increase asthma risk in offspring. Thus, risk factors for asthma should be sought in both parents and before conception. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/14456 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | CC BY-NC 4.0: Namensnennung - Nicht kommerziell 4.0 International |
| Departement: | Gesundheit |
| Organisationseinheit: | Institut für Public Health (IPH) |
| Enthalten in den Sammlungen: | Publikationen Gesundheit |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| 2018_Accordini-etal_Three-generation-study-on-the-association-of-tobacco-smoking-with-asthma.pdf | 766.77 kB | Adobe PDF |  Öffnen/Anzeigen |
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Accordini, S., Calciano, L., Johannessen, A., Portas, L., Benediktsdóttir, B., Bertelsen, R. J., Bråbäck, L., Carsin, A.-E., Dharmage, S. C., Dratva, J., Forsberg, B., Gomez Real, F., Heinrich, J., Holloway, J. W., Holm, M., Janson, C., Jögi, R., Leynaert, B., Malinovschi, A., et al. (2018). A three-generation study on the association of tobacco smoking with asthma. International Journal of Epidemiology, 47(4), 1106–1117. https://doi.org/10.1093/ije/dyy031
Accordini, S. et al. (2018) ‘A three-generation study on the association of tobacco smoking with asthma’, International Journal of Epidemiology, 47(4), pp. 1106–1117. Available at: https://doi.org/10.1093/ije/dyy031.
S. Accordini et al., “A three-generation study on the association of tobacco smoking with asthma,” International Journal of Epidemiology, vol. 47, no. 4, pp. 1106–1117, 2018, doi: 10.1093/ije/dyy031.
ACCORDINI, Simone, Lucia CALCIANO, Ane JOHANNESSEN, Laura PORTAS, Bryndis BENEDIKTSDÓTTIR, Randi Jacobsen BERTELSEN, Lennart BRÅBÄCK, Anne-Elie CARSIN, Shyamali C DHARMAGE, Julia DRATVA, Bertil FORSBERG, Francisco GOMEZ REAL, Joachim HEINRICH, John W HOLLOWAY, Mathias HOLM, Christer JANSON, Rain JÖGI, Bénédicte LEYNAERT, Andrei MALINOVSCHI, Alessandro MARCON, Jesús MARTÍNEZ-MORATALLA ROVIRA, Chantal RAHERISON, José Luis SÁNCHEZ-RAMOS, Vivi SCHLÜNSSEN, Roberto BONO, Angelo G CORSICO, Pascal DEMOLY, Sandra DORADO ARENAS, Dennis NOWAK, Isabelle PIN, Joost WEYLER, Deborah JARVIS und Cecilie SVANES, 2018. A three-generation study on the association of tobacco smoking with asthma. International Journal of Epidemiology. 2018. Bd. 47, Nr. 4, S. 1106–1117. DOI 10.1093/ije/dyy031
Accordini, Simone, Lucia Calciano, Ane Johannessen, Laura Portas, Bryndis Benediktsdóttir, Randi Jacobsen Bertelsen, Lennart Bråbäck, et al. 2018. “A Three-Generation Study on the Association of Tobacco Smoking with Asthma.” International Journal of Epidemiology 47 (4): 1106–17. https://doi.org/10.1093/ije/dyy031.
Accordini, Simone, et al. “A Three-Generation Study on the Association of Tobacco Smoking with Asthma.” International Journal of Epidemiology, vol. 47, no. 4, 2018, pp. 1106–17, https://doi.org/10.1093/ije/dyy031.
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